i-Human Patients® Cases

Comprehensive simulated patient encounters.

Development and assessment of diagnostic reasoning skills requires problem-specific solutions, knowledge, and experience linked directly to presenting symptoms and diseases. Mastery of these skills also requires objective evidence-based feedback, active engagement and hundreds of encounters representing a broad variety and complexity of problems. We believe that these requirements are best achieved through computer-based diagnostic decision simulations.

Choose the case approach that best meets your needs.

Over 500 Published Cases Available

Select from free “Share and Share-Alike” cases and “Premium” cases sponsored by the AMA, Reliance Foundation and others

Author Your Own Cases

Create your own cases using our point-and-click online authoring system

Make Derivative Works Of Existing “Share And Share-Alike” Cases

Create & share derivative works under a Creative Commons “Share & Share Alike” license

“Share and Share Alike” Cases

Cases developed with no sponsorship and made freely available to subscribers of the i-Human Patients Case Player under the Creative Commons License “Share and Share Alike.”

Premium Cases

These are peer reviewed cases developed by clinicians, educators, and leading medical institutions under the financial sponsorship of a third party, such as the American Medical Association and Reliance Foundation for a nominal subscription fee.

Create Custom Cases

Define learning and assessment objectives for any clinical experience level. Create your own simulated patient cases using our point-and-click authoring system. Access to thousands of medical media assets from our repository including ECGs, radiographs, histopathology slides, illustrations, or upload and use your own. Embed assessment rubrics (MCQ, T/F, matching, concept diagrams) and learning exercises related to the clinical and/or basic science concepts underlying the case. Retain our clinical educators to help develop, customize and quality assure your cases.

Create and Share Derivative Works

Use our point-and-click authoring system to customize existing cases to specific institutional needs, when permitted by the original author’s Creative Commons License. Custom or derivative works may be shared with other subscribing institutions, if desired.

Standard Cases

Number of cases by body system

We offer more than 115 standard share and share alike and premium cases to subscribers.

  • Cardiovascular
    20 cases
  • Endocrine
    7 cases
  • Gastrointestinal
    17 cases
  • Hematologic
    8 cases
  • Immunologic
    10 cases
  • Integumentary
    4 cases
  • Lymphatic
    2 cases
  • Musculoskeletal
    10 cases
  • Neurologic
    8 cases
  • Psychiatric
    12 cases
  • Reproductive
    6 cases
  • Pulmonary
    8 cases
  • Renal
    4 cases

Sampling of “Share and Share Alike” and “Premium” case topics available to i-Human Patients subscribers:

Selected Chief Complaints & Symptoms
  • Abdominal discomfort and ankle swelling
  • Abdominal discomfort/fatigue/muscle pain
  • Abnormal liver enzymes
  • Abdominal pain and fever
  • Abdominal pain with confusion
  • Acute abdominal pain
  • Acute chest pain
  • Acute chest pressure and diaphoresis
  • Acute kidney injury
  • Acute neurological deficit
  • Acute onset chest pain and dyspnea
  • Acute severe sharp stabbing chest pain
  • Altered level of consciousness
  • Altered mental status
  • Anemia
  • Anorexia
  • Arm weakness
  • Back pain
  • Back and abdominal pain
  • Back pain/orthopnea/DOE/night sweats
  • Breast lump
  • Chest pain – pleuritic
  • Chest pain – reproducible
  • Chest pain – tearing
  • Chest pain – unrelieved
  • Chest pain with exertion
  • Chronic cough and fatigue
  • Coffee – ground vomit
  • Colicky abdominal pain
  • Confusion and fatigue
  • Confusion – progressive
  • Cough and fever
  • Decreased urine output
  • Delirium
  • Depression
  • Diarrhea
  • Diarrhea with fever and abdominal pain
  • Difficulty swallowing
  • Dizziness
  • Dyspnea – acute
  • Dyspnea – chronic progressive
  • Dyspnea – exertional
  • Dyspnea and fatigue
  • Dyspnea with productive cough
  • Dyspnea with weight gain
  • Dysuria
  • Dysuria and vaginal discharge
  • Exertional chest pressure
  • Fatigue
  • Fatigue and malaise
  • Fatigue/anorexia and RUQ abdominal pain
  • Fatigue/myalgia/dyspnea and fever
  • Fatigue with increased urination
  • Fever
  • Fever/chills/new onset facial droop
  • Groin pain
  • Headache
  • Hematemesis
  • Hematochezia
  • Heart pounding and fatigue
  • High blood pressure
  • High blood pressure refractory to Rx
  • Hyponatremia
  • Incontinence
  • Increased fatigue and dyspnea
  • Infertility
  • Joint pain
  • Knee pain
  • Lightheadedness
  • Lower abdominal and testicular pain
  • Left upper quadrant (LUQ) pain
  • Muscle pain
  • Nausea and fatigue
  • Nausea and vomiting
  • Near syncope
  • Palpitations/fatigue/dyspnea
  • Persistent dry cough
  • Progressive fatigue with dyspnea
  • Progressive weakness with fatigue
  • Rash
  • Rash; progressive fever/malaise
  • Recent weight loss
  • Rectal bleeding
  • Right flank pain/fever/nausea and recurrent vomiting
  • Sore throat
  • Stomach discomfort/fatigue and melena
  • Swollen hands and feet
  • Syncope
  • Term pregnancy/dyspnea
  • Vertigo
Selected Diagnoses
  • Acute appendicitis
  • Acute infectious gastroenteritis
  • Acute kidney injury
  • Acute mesenteric ischemia
  • Acute mitral regurgitation
  • Acute myocardial infarction
  • Acute pyelonephritis
  • Acute renal failure
  • Adjustment disorder
  • Alcohol abuse
  • Alcoholic cirrhosis
  • Alzheimer’s disease
  • Angiodysplasia
  • Anorexia nervosa
  • Aortic dissection
  • Aortic stenosis
  • Aortoenteric fistula
  • Atrial fibrillation
  • Atrial septal defect
  • Attention deficit hyperactivity disorder (ADD/ADHD)
  • Bipolar disorder
  • Borderline personality disorder
  • Breast cancer
  • Cardiac arrest – ventricular fibrillation
  • Celiac disease
  • Choledocholithiasis
  • Chronic renal failure
  • Colon cancer
  • Congestive heart failure
  • Conversion disorder
  • COPD/emphysema with cor pulmonale
  • Costochondritis
  • Depression
  • Diabetes mellitus type I
  • Diabetes mellitus type II
  • Diabetic ketoacidosis
  • Displaced ovaries secondary to abdominal adhesions
  • Diverticulitis
  • Endocarditis
  • Esophageal neoplasm
  • Esophageal varices
  • Essential hypertension
  • Gonorrhea
  • Gout
  • Gram negative diarrhea
  • Granulomatosis with polyangiitis
  • Group A streptococcal pharyngitis
  • Heart failure
  • Hemorrhagic stroke
  • Hepatitis
  • Herniated lumbar disk
  • HIV
  • Hypertension
  • Hyponatremia
  • Incarcerated hernia
  • Influenza
  • Infectious colitis
  • Iron deficiency anemia
  • Lateral medullary infarct
  • Metastatic cancer
  • Migraine
  • Multiple myeloma
  • Multiple sclerosis
  • Myocardial infarction
  • Myocardial infarction progressing to ventricular fibrillation
  • Obsessive – compulsive disorder (OCD)
  • Osteoarthritis
  • Osteomyelitis
  • Panic disorder
  • Peptic ulcer disease
  • Peripartum cardiomyopahty
  • Pneumonia
  • Primary aldosteronism
  • PTSD
  • Pulmonary embolism
  • Pyelonephritis
  • Renal artery stenosis
  • Schizophrenia
  • Septic shock
  • SIADH
  • Sickle cell anemia
  • Small-bowel obstruction
  • Stable angina
  • Subarachnoid hemorrhage
  • Systemic lupus erythematosus
  • T-Cell lymphoma
  • Thoracic aortic dissection
  • Vertebral compression fracture – metastatic cancer
  • Unstable angina
  • Wegener’s granulomatosis